23 4 / 2014

sweet-pea-soup:

crossing off one of 70 or so comic ideas I’ve been saving up over the past 5+ years

sweet-pea-soup:

crossing off one of 70 or so comic ideas I’ve been saving up over the past 5+ years

(via thatsmybreastsnotmypinlanyard)

22 4 / 2014

rainbowsparklekittens:

you can treat me like a princess and i’ll treat you like a princess we can be gay princesses together

(Source: rainbowsnowflakekittens, via gloomthkin)

22 4 / 2014

ravclaw:

my essay isn’t done but i sure am

(Source: tiniestleaf, via gayisthenew-black)

22 4 / 2014

queeflto:

yes i lift.. im an elevator thats all i do

(via gayisthenew-black)

22 4 / 2014

22 4 / 2014

knightlypatroclus:

do you ever have sudden Waves of Emotion for nisus and euryalus?

of course you do.  don’t lie to me

(via gloomthkin)

22 4 / 2014

kneelbeforemistressphil:

bluepuffycat:

casinpanties:

angelmojo:

the first harry potter book is only 76k words

i’ve read gay fan fic longer than harry potter

image

i’ve written gay fan fic

longer than harry potter

I’ve written gay fan fic about Harry Potter longer than Harry Potter

bless you all

(Source: casterlyrox, via herawesomenessmaria)

21 4 / 2014

"College kids literally don’t care about walking in the way of cars at school because we’re like “hit me i don’t care pay my tuition.”"

(via cdeathhh)

"Hit me my thesis is due in 12 hours and I haven’t started it"

"Hit me I have a final in an hour and I didn’t study"

"Hit me I’ve been on a 24 hour drinking binge and I’m invincible"

(via combatbabycomeback)

"Hit me. You’re a university vehicle and I’ll get free tuition."

(via thisisgoodbyegravity)

(via fromhere-tonow-toyou)

21 4 / 2014

21 4 / 2014

knightscrest:

Ur what we in the scientific community call “a lil bitch”

(via fromhere-tonow-toyou)

20 4 / 2014

tallestsilver:

hiddlestalker:

johnthemod1:

vhanstiel:

girlatsunrise:

doppelrahmstufe:

(X)

WE FOUND IT.
WE FOUND BETELGEUSE FIVE.

Remember when we read about touchscreen and ebook before those things exist? Now if you’ll excuse me, I need to find myself a nice towel.

OH.
MY.
GOD.

EVERYBODY GRAB YOUR TOWELS


Don’t panic. I repeat. DON’T. PANIC. 
Ford, stoppit, You’re turning into a penguin. 

tallestsilver:

hiddlestalker:

johnthemod1:

vhanstiel:

girlatsunrise:

doppelrahmstufe:

(X)

WE FOUND IT.

WE FOUND BETELGEUSE FIVE.

Remember when we read about touchscreen and ebook before those things exist? Now if you’ll excuse me, I need to find myself a nice towel.

OH.

MY.

GOD.

EVERYBODY GRAB YOUR TOWELS

Don’t panic. I repeat. DON’T. PANIC. 

Ford, stoppit, You’re turning into a penguin. 

(via gloomthkin)

20 4 / 2014

i-heart-histo:


The Seamless Blood Vessel by i-heart-histo
For fans of the Seamless Gut, Seamless Lung and Seamless Ovary.
A generalized blood vessel has a wall that is composed of three tunics:
an inner tunica intima (endothelium, subendothelium and internal elastic lamina)
a middle tunica media (smooth muscle and an external elastic lamina)
an outer tunica adventitia (connective tissue with a vaso vasorum/nervi vasorum)
As you progress from arterial to venous vasculature, each vessel type of decreasing/increasing diameter differs in the organization of these three layers making classification simple. Here is a guide to help you:
1. Heart wall
The largest ‘vessel’. Its tunica intima is known as the endocardium; its tunica media is known as the myocardium and is composed of cardiac muscle; and its tunica adventitia forms an outer pericardium composed of adipose tissue within which is embedded its vaso vasorum (aka the coronary arteries/cardiac veins). The pericardium is also lined with a visceral serous mesothelium that secretes pericardial fluid into the pericardial cavity.
Key identifying feature: Myocardium composed of cardiac muscle
2. Elastic artery (large)
The aorta is an example of a large/elastic artery. It has a thick tunica media composed of smooth muscle and distinctive elastin fibers that allow the vessel to stretch during ventricular systole and recoil during diastole to assist in propulsion of blood through the vascular system.
Key identifying feature: Tunica media contains thick wavy elastin fibers
3. Muscular/Distributing artery (medium)
Medium arteries have a very thick tunica media composed of smooth muscle to maintain vascular resistance and blood pressure. The tunica intima has a prominent circumscribing internal elastic lamina and the tunica media has a prominent circumscribing external elastic lamina.
Key identifying feature: Prominent internal and external elastic laminae
4. Muscular/Distributing artery (small)
As arteries get smaller in diameter, the smooth muscle layer gets thinner and the internal elastic lamina begins to diminished or is absent. As an arbitrary rule of thumb, if you see more than 6 layers of smooth muscle and an internal elastic lamina it is a small artery (that’s the i-heart-histo rule, but some textbooks would set this number higher or lower – matter of preference).
Key identifying feature: 6+ layers of smooth muscle and a prominent internal elastic lamina
 5. Arteriole (large)
Despite the small size of these vessels the tunica media is the most predominant layer. It is less than 6 smooth muscle cells thick. Larger arterioles often have a distinctive internal elastic lamina.
Key identifying feature: Less than 6 layers of smooth muscle, may be an internal elastic lamina
6. Arteriole (small)
Once again, these have a large tunica media for their very small size, Think around 3 smooth muscle cells thick. Some may have an internal elastic lamina although it is usually absent at this vessel size.
Key identifying feature: Around three layers of smooth muscle, indistinct/absent internal elastic lamina.
Capillary (not shown)
Venule (not shown)
7. Muscular vein (small)
Small veins have a distinctly thick tunica adventitia when compared to a thin tunica media which is around 3-4 smooth muscle cells thick. Considering the size of the vessel is equivalent to a small artery, it has the tunica media of a small arteriole. Puny! Oh and if you are very lucky you might even see valves!
Key identifying feature: Thin tunica media with around 3 layers of smooth muscle, but a very thick tunica adventitia.
8. Muscular vein (medium)
Medium veins are the equivalent in size to a medium artery but only have a tunica media thickness of a large arteriole. The tunica adventitia of these vessels is by far the thickest layer. Once again, fingers crossed to see an elusive valve.
Key identifying feature: Thin tunica media with around 6 layers of smooth muscle, but a very thick tunica adventitia.
9. Vena cava
Equivalent in size to the aorta but with a thin tunica media. The connective tissue tunica adventitia predominates and contains distinctive arrays of longitudinal muscle fibers.
Key identifying feature: Thin tunica media. Very thick tunica adventitia that contains longitudinally arranged smooth muscle.
Happy classifying!!
i-h-h

i-heart-histo:

The Seamless Blood Vessel by i-heart-histo

For fans of the Seamless Gut, Seamless Lung and Seamless Ovary.

A generalized blood vessel has a wall that is composed of three tunics:

  • an inner tunica intima (endothelium, subendothelium and internal elastic lamina)
  • a middle tunica media (smooth muscle and an external elastic lamina)
  • an outer tunica adventitia (connective tissue with a vaso vasorum/nervi vasorum)

As you progress from arterial to venous vasculature, each vessel type of decreasing/increasing diameter differs in the organization of these three layers making classification simple. Here is a guide to help you:

1. Heart wall

The largest ‘vessel’. Its tunica intima is known as the endocardium; its tunica media is known as the myocardium and is composed of cardiac muscle; and its tunica adventitia forms an outer pericardium composed of adipose tissue within which is embedded its vaso vasorum (aka the coronary arteries/cardiac veins). The pericardium is also lined with a visceral serous mesothelium that secretes pericardial fluid into the pericardial cavity.

  • Key identifying feature: Myocardium composed of cardiac muscle

2. Elastic artery (large)

The aorta is an example of a large/elastic artery. It has a thick tunica media composed of smooth muscle and distinctive elastin fibers that allow the vessel to stretch during ventricular systole and recoil during diastole to assist in propulsion of blood through the vascular system.

  • Key identifying feature: Tunica media contains thick wavy elastin fibers

3. Muscular/Distributing artery (medium)

Medium arteries have a very thick tunica media composed of smooth muscle to maintain vascular resistance and blood pressure. The tunica intima has a prominent circumscribing internal elastic lamina and the tunica media has a prominent circumscribing external elastic lamina.

  • Key identifying feature: Prominent internal and external elastic laminae

4. Muscular/Distributing artery (small)

As arteries get smaller in diameter, the smooth muscle layer gets thinner and the internal elastic lamina begins to diminished or is absent. As an arbitrary rule of thumb, if you see more than 6 layers of smooth muscle and an internal elastic lamina it is a small artery (that’s the i-heart-histo rule, but some textbooks would set this number higher or lower – matter of preference).

  • Key identifying feature: 6+ layers of smooth muscle and a prominent internal elastic lamina

 5. Arteriole (large)

Despite the small size of these vessels the tunica media is the most predominant layer. It is less than 6 smooth muscle cells thick. Larger arterioles often have a distinctive internal elastic lamina.

  • Key identifying feature: Less than 6 layers of smooth muscle, may be an internal elastic lamina

6. Arteriole (small)

Once again, these have a large tunica media for their very small size, Think around 3 smooth muscle cells thick. Some may have an internal elastic lamina although it is usually absent at this vessel size.

  • Key identifying feature: Around three layers of smooth muscle, indistinct/absent internal elastic lamina.

Capillary (not shown)

Venule (not shown)

7. Muscular vein (small)

Small veins have a distinctly thick tunica adventitia when compared to a thin tunica media which is around 3-4 smooth muscle cells thick. Considering the size of the vessel is equivalent to a small artery, it has the tunica media of a small arteriole. Puny! Oh and if you are very lucky you might even see valves!

  • Key identifying feature: Thin tunica media with around 3 layers of smooth muscle, but a very thick tunica adventitia.

8. Muscular vein (medium)

Medium veins are the equivalent in size to a medium artery but only have a tunica media thickness of a large arteriole. The tunica adventitia of these vessels is by far the thickest layer. Once again, fingers crossed to see an elusive valve.

  • Key identifying feature: Thin tunica media with around 6 layers of smooth muscle, but a very thick tunica adventitia.

9. Vena cava

Equivalent in size to the aorta but with a thin tunica media. The connective tissue tunica adventitia predominates and contains distinctive arrays of longitudinal muscle fibers.

  • Key identifying feature: Thin tunica media. Very thick tunica adventitia that contains longitudinally arranged smooth muscle.

Happy classifying!!

i-h-h

(via scinerds)

20 4 / 2014

raaahleigh:

here have some 5am selfies

(via wolfthicket)

19 4 / 2014

dawnoftheclarineticorns:

mandyn10:

music not mickey 

all I saw was the music at first and then I read the caption and I can’t unsee it

dawnoftheclarineticorns:

mandyn10:

music not mickey 

all I saw was the music at first and then I read the caption and I can’t unsee it

(Source: manderzz59334, via fromhere-tonow-toyou)

19 4 / 2014

myrtlewilson:

modern au achilles feels the need to tell everyone how great patroclus is and they’re all like “bro he’s literally just reading a book right now,” and achilles just stares at him wonderstruck like “yeah but look at the way he artfully turns the pages and how engrossed he is in his reading, he’s such a scholar he’s so smart,” like boy u got it bad 

(via gloomthkin)