20 4 / 2014

tallestsilver:

hiddlestalker:

johnthemod1:

vhanstiel:

girlatsunrise:

doppelrahmstufe:

(X)

WE FOUND IT.
WE FOUND BETELGEUSE FIVE.

Remember when we read about touchscreen and ebook before those things exist? Now if you’ll excuse me, I need to find myself a nice towel.

OH.
MY.
GOD.

EVERYBODY GRAB YOUR TOWELS


Don’t panic. I repeat. DON’T. PANIC. 
Ford, stoppit, You’re turning into a penguin. 

tallestsilver:

hiddlestalker:

johnthemod1:

vhanstiel:

girlatsunrise:

doppelrahmstufe:

(X)

WE FOUND IT.

WE FOUND BETELGEUSE FIVE.

Remember when we read about touchscreen and ebook before those things exist? Now if you’ll excuse me, I need to find myself a nice towel.

OH.

MY.

GOD.

EVERYBODY GRAB YOUR TOWELS

Don’t panic. I repeat. DON’T. PANIC. 

Ford, stoppit, You’re turning into a penguin. 

(via gloomthkin)

20 4 / 2014

i-heart-histo:


The Seamless Blood Vessel by i-heart-histo
For fans of the Seamless Gut, Seamless Lung and Seamless Ovary.
A generalized blood vessel has a wall that is composed of three tunics:
an inner tunica intima (endothelium, subendothelium and internal elastic lamina)
a middle tunica media (smooth muscle and an external elastic lamina)
an outer tunica adventitia (connective tissue with a vaso vasorum/nervi vasorum)
As you progress from arterial to venous vasculature, each vessel type of decreasing/increasing diameter differs in the organization of these three layers making classification simple. Here is a guide to help you:
1. Heart wall
The largest ‘vessel’. Its tunica intima is known as the endocardium; its tunica media is known as the myocardium and is composed of cardiac muscle; and its tunica adventitia forms an outer pericardium composed of adipose tissue within which is embedded its vaso vasorum (aka the coronary arteries/cardiac veins). The pericardium is also lined with a visceral serous mesothelium that secretes pericardial fluid into the pericardial cavity.
Key identifying feature: Myocardium composed of cardiac muscle
2. Elastic artery (large)
The aorta is an example of a large/elastic artery. It has a thick tunica media composed of smooth muscle and distinctive elastin fibers that allow the vessel to stretch during ventricular systole and recoil during diastole to assist in propulsion of blood through the vascular system.
Key identifying feature: Tunica media contains thick wavy elastin fibers
3. Muscular/Distributing artery (medium)
Medium arteries have a very thick tunica media composed of smooth muscle to maintain vascular resistance and blood pressure. The tunica intima has a prominent circumscribing internal elastic lamina and the tunica media has a prominent circumscribing external elastic lamina.
Key identifying feature: Prominent internal and external elastic laminae
4. Muscular/Distributing artery (small)
As arteries get smaller in diameter, the smooth muscle layer gets thinner and the internal elastic lamina begins to diminished or is absent. As an arbitrary rule of thumb, if you see more than 6 layers of smooth muscle and an internal elastic lamina it is a small artery (that’s the i-heart-histo rule, but some textbooks would set this number higher or lower – matter of preference).
Key identifying feature: 6+ layers of smooth muscle and a prominent internal elastic lamina
 5. Arteriole (large)
Despite the small size of these vessels the tunica media is the most predominant layer. It is less than 6 smooth muscle cells thick. Larger arterioles often have a distinctive internal elastic lamina.
Key identifying feature: Less than 6 layers of smooth muscle, may be an internal elastic lamina
6. Arteriole (small)
Once again, these have a large tunica media for their very small size, Think around 3 smooth muscle cells thick. Some may have an internal elastic lamina although it is usually absent at this vessel size.
Key identifying feature: Around three layers of smooth muscle, indistinct/absent internal elastic lamina.
Capillary (not shown)
Venule (not shown)
7. Muscular vein (small)
Small veins have a distinctly thick tunica adventitia when compared to a thin tunica media which is around 3-4 smooth muscle cells thick. Considering the size of the vessel is equivalent to a small artery, it has the tunica media of a small arteriole. Puny! Oh and if you are very lucky you might even see valves!
Key identifying feature: Thin tunica media with around 3 layers of smooth muscle, but a very thick tunica adventitia.
8. Muscular vein (medium)
Medium veins are the equivalent in size to a medium artery but only have a tunica media thickness of a large arteriole. The tunica adventitia of these vessels is by far the thickest layer. Once again, fingers crossed to see an elusive valve.
Key identifying feature: Thin tunica media with around 6 layers of smooth muscle, but a very thick tunica adventitia.
9. Vena cava
Equivalent in size to the aorta but with a thin tunica media. The connective tissue tunica adventitia predominates and contains distinctive arrays of longitudinal muscle fibers.
Key identifying feature: Thin tunica media. Very thick tunica adventitia that contains longitudinally arranged smooth muscle.
Happy classifying!!
i-h-h

i-heart-histo:

The Seamless Blood Vessel by i-heart-histo

For fans of the Seamless Gut, Seamless Lung and Seamless Ovary.

A generalized blood vessel has a wall that is composed of three tunics:

  • an inner tunica intima (endothelium, subendothelium and internal elastic lamina)
  • a middle tunica media (smooth muscle and an external elastic lamina)
  • an outer tunica adventitia (connective tissue with a vaso vasorum/nervi vasorum)

As you progress from arterial to venous vasculature, each vessel type of decreasing/increasing diameter differs in the organization of these three layers making classification simple. Here is a guide to help you:

1. Heart wall

The largest ‘vessel’. Its tunica intima is known as the endocardium; its tunica media is known as the myocardium and is composed of cardiac muscle; and its tunica adventitia forms an outer pericardium composed of adipose tissue within which is embedded its vaso vasorum (aka the coronary arteries/cardiac veins). The pericardium is also lined with a visceral serous mesothelium that secretes pericardial fluid into the pericardial cavity.

  • Key identifying feature: Myocardium composed of cardiac muscle

2. Elastic artery (large)

The aorta is an example of a large/elastic artery. It has a thick tunica media composed of smooth muscle and distinctive elastin fibers that allow the vessel to stretch during ventricular systole and recoil during diastole to assist in propulsion of blood through the vascular system.

  • Key identifying feature: Tunica media contains thick wavy elastin fibers

3. Muscular/Distributing artery (medium)

Medium arteries have a very thick tunica media composed of smooth muscle to maintain vascular resistance and blood pressure. The tunica intima has a prominent circumscribing internal elastic lamina and the tunica media has a prominent circumscribing external elastic lamina.

  • Key identifying feature: Prominent internal and external elastic laminae

4. Muscular/Distributing artery (small)

As arteries get smaller in diameter, the smooth muscle layer gets thinner and the internal elastic lamina begins to diminished or is absent. As an arbitrary rule of thumb, if you see more than 6 layers of smooth muscle and an internal elastic lamina it is a small artery (that’s the i-heart-histo rule, but some textbooks would set this number higher or lower – matter of preference).

  • Key identifying feature: 6+ layers of smooth muscle and a prominent internal elastic lamina

 5. Arteriole (large)

Despite the small size of these vessels the tunica media is the most predominant layer. It is less than 6 smooth muscle cells thick. Larger arterioles often have a distinctive internal elastic lamina.

  • Key identifying feature: Less than 6 layers of smooth muscle, may be an internal elastic lamina

6. Arteriole (small)

Once again, these have a large tunica media for their very small size, Think around 3 smooth muscle cells thick. Some may have an internal elastic lamina although it is usually absent at this vessel size.

  • Key identifying feature: Around three layers of smooth muscle, indistinct/absent internal elastic lamina.

Capillary (not shown)

Venule (not shown)

7. Muscular vein (small)

Small veins have a distinctly thick tunica adventitia when compared to a thin tunica media which is around 3-4 smooth muscle cells thick. Considering the size of the vessel is equivalent to a small artery, it has the tunica media of a small arteriole. Puny! Oh and if you are very lucky you might even see valves!

  • Key identifying feature: Thin tunica media with around 3 layers of smooth muscle, but a very thick tunica adventitia.

8. Muscular vein (medium)

Medium veins are the equivalent in size to a medium artery but only have a tunica media thickness of a large arteriole. The tunica adventitia of these vessels is by far the thickest layer. Once again, fingers crossed to see an elusive valve.

  • Key identifying feature: Thin tunica media with around 6 layers of smooth muscle, but a very thick tunica adventitia.

9. Vena cava

Equivalent in size to the aorta but with a thin tunica media. The connective tissue tunica adventitia predominates and contains distinctive arrays of longitudinal muscle fibers.

  • Key identifying feature: Thin tunica media. Very thick tunica adventitia that contains longitudinally arranged smooth muscle.

Happy classifying!!

i-h-h

(via scinerds)

20 4 / 2014

raaahleigh:

here have some 5am selfies

(via 1800shitbody)

19 4 / 2014

dawnoftheclarineticorns:

mandyn10:

music not mickey 

all I saw was the music at first and then I read the caption and I can’t unsee it

dawnoftheclarineticorns:

mandyn10:

music not mickey 

all I saw was the music at first and then I read the caption and I can’t unsee it

(Source: manderzz59334, via fromhere-tonow-toyou)

19 4 / 2014

myrtlewilson:

modern au achilles feels the need to tell everyone how great patroclus is and they’re all like “bro he’s literally just reading a book right now,” and achilles just stares at him wonderstruck like “yeah but look at the way he artfully turns the pages and how engrossed he is in his reading, he’s such a scholar he’s so smart,” like boy u got it bad 

(via gloomthkin)

19 4 / 2014

exit the womb they said

life will be great they said

(via gloomthkin)

18 4 / 2014

lightspeedsound:

1) How to jig (at least how to look like I’m jigging)

2) How to calm myself down with meditative thought 

3) How to greet a horse 

4) How to spin 

5) How to survive a marauding army of enslaved soul robots and kill a necromancer with just the aid of a few really hot dudes, some horses, and a couple of badass dogs

(via gloomthkin)

18 4 / 2014

dutchster:

i accidentally spilled monster energy drink in my fish bowl and now my goldfish won’t stop saying “bro” and keeps flexing its fins

(via gayisthenew-black)

18 4 / 2014

nuclearpiss:

is this supernatural

(Source: stuckwithyoutubers, via herawesomenessmaria)

18 4 / 2014

couple-of-dumbasses:

leviisacutelittleshit:

colourfulpantsandarainbowhat:

beggars-opera:

colourfulpantsandarainbowhat:

WHY DO PEOPLE CALL IT FUCK, MARRY, KILL WHEN THEY COULD CALL IT BED, WED, BEHEAD

easy there henry

whos henry what thef uck?

*faint laughter from Britian*

*history teachers crying*

(via plinythesassier)

18 4 / 2014

18 4 / 2014

missingkitsune:

"There there, I’m sorry I scared you. *pats and kisses* you’re a good dog, good dog."

missingkitsune:

"There there, I’m sorry I scared you. *pats and kisses* you’re a good dog, good dog."

(via herawesomenessmaria)

18 4 / 2014

Photographer Bobby-Jo Clow [website | facebook] found herself face-to-face with a cheetah cub who approached her Landrover while on safari at the Serengeti National Park in Tanzania. She documented the curious cat’s looks of wonder and trepidation at the vehicle and its passengers.

[article | mymodernmet]

(via thefrogman)

18 4 / 2014

18 4 / 2014

thelegendofkungjew:

doxian:

d-dinosaur:

rknjl:

newvagabond:

NO “TELEPHONES”. TALK TO EACH OTHER. FACE TO FACE ONLY. WRITE A LETTER. SEND A TELEGRAM TO YOUR MOM. PRETEND IT’S 1860. LIVE.

NO ‘WRITING’… TALK TO EACH OTHER. THROW A ROCK AT YOUR MOM. PRETEND IT’S 10,000 BCE.  LIVE.

URGGA. ROU GRAAURH. RUH.
<SMACKS HANDS ON WALL WITH PAINT.>

NO ‘HIGHER BRAIN FUNCTIONS’ …USE YOUR REPTILIAN BRAIN
EAT YOUR MOM’S CORPSE SHE DIED TO PROVIDE YOU WITH SUSTENANCE
PRETEND YOU HAVE JUST AROSE FROM THE SEA
SURVIVE

NO “MULTICELLULAR TRAITS”….. USE YOUR SYMBIOTIC MITOCHONDRIA
REPRODUCE ASEXUALLY, YOU’RE YOUR OWN PARENT
PRETEND IT’S 2BYA
EVOLVE

thelegendofkungjew:

doxian:

d-dinosaur:

rknjl:

newvagabond:

NO “TELEPHONES”. TALK TO EACH OTHER. FACE TO FACE ONLY. WRITE A LETTER. SEND A TELEGRAM TO YOUR MOM. PRETEND IT’S 1860. LIVE.

NO ‘WRITING’… TALK TO EACH OTHER. THROW A ROCK AT YOUR MOM. PRETEND IT’S 10,000 BCE.  LIVE.

URGGA. ROU GRAAURH. RUH.

<SMACKS HANDS ON WALL WITH PAINT.>

NO ‘HIGHER BRAIN FUNCTIONS’ …USE YOUR REPTILIAN BRAIN

EAT YOUR MOM’S CORPSE SHE DIED TO PROVIDE YOU WITH SUSTENANCE

PRETEND YOU HAVE JUST AROSE FROM THE SEA

SURVIVE

NO “MULTICELLULAR TRAITS”….. USE YOUR SYMBIOTIC MITOCHONDRIA

REPRODUCE ASEXUALLY, YOU’RE YOUR OWN PARENT

PRETEND IT’S 2BYA

EVOLVE

(Source: agirlandhisplatypus, via mypocketshurt90)